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A.I. Solutions for your Bioprocess

Precision. Intelligence. BioValue.

Digital Twins in bioprocess monitoring and control

About

Digital automation, A. I. and Control solutions 

At Norferma AS, we combine cutting-edge research with hands-on industry experience to modernize bioprocessing from the ground up. Backed by over €20 million in EU-funded projects, partners like BASF & Borregaard, and two decades of control-systems expertise, we deliver proven digital automation solutions. Below are a few highlights of our credentials and impact:

  1. Our Origins

    • Spin-off from NTNU’s iCulture & iFermenter (€20 M+)

    • Built on 15+ years of academic research

  2. The Founder

    • Prof. Nadav Bar, PhD Engineering Cybernetics, 20+ years in control systems

  3. Our Mission

    • Eliminate ± 25-50 % yield variability in bioprocessing

    • Provide stable and consistent (± 1-5%) product composition
    • Automate and digitalize fermentation & extraction

  4. Our Expertise & Proof

    • Digital twin control reduced downtime by 40% in pilot plant, Belgium

    • AI-driven bioprocess boosted yields by 125% (Anti-microbial peptides)

    • Published in international journals (e.g. Bioprocess Engineering Journal, 2024)

  5. Why Trust Us?

    • EU-backed track record (iCulture, iFermenter, SafeFood, BacPress)

    • NTNU-affiliated R&D team of 8 engineers and scientists

Why work with us

Expert automation, A.I. optimization and control Solutions

Future-Proof Innovation

Stay ahead with AI-driven control strategies and scalable workflows that evolve alongside your process—ensuring you maintain regulatory compliance and competitive edge.

Exceptional Customer Service

We dive deep into your data, pinpoint critical control points, and implement custom solutions that drive consistency, yield, and quality—every batch, every time.

Unrivaled Bioprocess Mastery

We don’t just deliver tools; we build a unified platform that connects your lab- and plant-scale equipment, software, and analytics. From seamless instrumentation integration with Siemens microcontrollers, to real-time KPI dashboards and automated batch records, our system frees your team to focus on innovation, not IT headaches.

Norferma in the Media

BBC report of digital conversion


Seaweed is increasingly recognized not just as a sustainable biomass but as a versatile feedstock for precision digital bioprocessing. Norferma AS develops and deploys advanced biorefinery technologies that transform seaweed into high-value products across the food, feed, pharmaceutical, and chemical industries.

bioprocess control platform for sustainable conversion of Seaweed and plants

Services

Empowering Your Automation Needs with Norferma AS

Design automation solutions

Optimize every stage of your fermentation or cell-culture workflow. Our end-to-end automation platform orchestrates pumps, sensors, pH control and data capture so your process runs seamlessly—24/7, with zero manual handoffs. Scale up reproducibly, reduce operator error and accelerate time-to-market.

Digital Extraction Bioprocesses

We recognize that extraction processes today have a limited control scope, mostly because biomass is highly variable but technically challenge to measure in real time. Therefore effective control of the bioprocess is limited. 


Digital extraction is an advanced bioprocessing approach that integrates real-time sensory data (e.g. spectroscopy), sofware and hardware that form digital twins, and AI-driven control algorithms to optimize the recovery of valuable compounds from biomass. By continuously monitoring key parameters—such as biomass composition, temperature, pH, solvent concentration, and flow rates—a digital extraction platform can dynamically adjust operating conditions to maximize yield and purity while minimizing energy use and waste. The result is a highly efficient, sustainable extraction workflow that delivers consistent, high-value products for food, feed, and chemical applications. We can digitalize your bioprocess today, contact us.

Digital Precision fermentation bioprocess
Automated bioprocess
model predictive control (MPC) biotech

Automation and Software development for fermentation processes

Centralize all your bioreactor telemetry, protocols and analytics in one cloud-native dashboard. Visualize live process KPIs, automate SOPs, trigger batch starts/stops and generate GMP-ready batch records—all with drag-and-drop ease. Integrate legacy equipment via OPC-UA, MQTT or RESTful APIs. 


Norferma AS develops both Precision Fermentation for batch, fed-batch and continuous operations. With a digital twin that observes the process, machine learning algorithms and feedback control, we are able to optimize your microbial production in real time. By continuously monitoring and adjusting key parameters, the process ensures high yield, efficiency, and consistency, enabling sustainable production of food, feed, and bio-based chemicals.



A.I. Solutions for Bioprocesses

Turn raw bioreactor data into predictive insights. Our ML-powered toolset learns your cell-growth patterns and feed-strategies to forecast yields, preempt deviations and optimize substrate feeds in real time. Deploy reinforcement-learning controllers that adapt on the fly—maximizing titer, purity and uptime.

Automated bioprocess sampling
zero-waste bioprocess

From early-stage development to full commercial launch, we deliver hands-on support at every milestone. We optimize upstream, diagnose scale-up bottlenecks, optimize critical parameters, validate automated workflows, and ensure regulatory compliance. Count on us for tailored training, on-site audits, and turnkey documentation to keep your bioprocess on track and on budget.

Process Performance Consulting & Support

Contact us

Innovate With Norferma

Contact us to discuss possibilities to introduce automation to your bioprocesses.


Professor Nadi S Bar, Founder and CEO.